Specter of Hatred is the first part of the Yshari Sanctum uberlevel complex, accessible from Caldeum and leads to the Dream of Anguish. On Destruction difficulty, the main boss Dul'Mephistos and the Earth Fiend sub-bosses have a chance to drop Bartuc's Blood and Tal Rasha's Talisman respectively, parts of the two sets required to fight Valthek, the Vizjerei Sorcerer, the final boss of Yshari Sanctum.

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