The Seat of Hatred is the final area of Act III where the player must kill Mephisto to progress to the fourth act. This area is accessible via the Durance of Hate and contains many elite monsters. There are 3 super unique monsters here excluding Mephisto. If where Mephisto is is considered the northern part of the map, Bloodmoon Soulfire lies in the western room, Bilefroth the Pit Master is in the eastern room, and Gorestone appears at the entrance to the large room containing the portal to the Pandemonium Fortress.

On Nightmare difficulty, Mephisto opens a portal to Kurast 3000 BA when he dies. The character must be at least level 80 to go to this location to complete the Ennead Challenge.

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