The Plains of Despair is the second area in Act IV, connected to the Outer Steppes through a staircase, and the City of the Damned.
Izual can be encountered in this area and opens a portal to the Diamond Gates upon being killed on Hell difficulty. On Nightmare difficulty, he drops the Catalyst of Learning, an item needed to turn sacred unique and set items into signets.
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Izual always spawns at this location
Spawn location
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