Somewhere in the Flayer Jungle lies the entrance into the Flayer Dungeon. Players need to explore the maze-like dungeon in order to obtain Khalim's Brain. The optional dungeon Swampy Pit, which leads to the uberlevels Proving Grounds and Vizjun is located there. The waypoint of the Flayer Jungle is always located near the Swampy Pit.
On Hell difficulty, killing the Vizier opens a portal to Caldeum, an uberquest hub in Act III.