Median XL: Sigma features the same difficulty levels as the vanilla Diablo II: Lord of Destruction. Killing Baal unlocks the next difficulty level for that character.
Note: The difficulties were previously known as Hatred, Terror and Destruction and were reverted to Normal, Nightmare and Hell in patch 1.0.0 (2019).
- Level range (regular game) : 1-50
The first and easiest difficulty level. Regular monsters range from 50 to 10K health and deal 1 to 200 damage. Their AI is not very bright and leech works at 1.4 effectiveness, which should be just fine considering the increased amount of damage characters can deal compared to the regular game.
- Level range (regular game) : 51-100
A significant step up in difficulty, regular monsters range from 10K to 100K health and deal 250 to 750 damage. Leech is reduced to 1/7 effectiveness. There is a 50% resistances penalty. If you can beat Nightmare, you have completed the regular game. You can expect to reach level 95-100 at the end of the Nightmare difficulty.
- Level range (regular game) : 105-150
Every monster is powerful and extremely aggressive. Regular monsters range from 100K to 300K health and deal 500 to 1000 damage, but uberquest monsters go far beyond that. Abandon all hope. Leech is reduced to 1/15 to make up for high attack damage at this point in the game and there's a 100% resistances penalty.
Sacred uniques and sets drop only in Hell difficulty.